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C2C announces new MD and Commercial Director

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Connect 2 Cleanrooms Ltd (C2C) has appointed Nicola Coull as its new Managing Director and Oliver Barker as Commercial Director.

C2C provides integrated cleanroom services and was acquired by USA-based Angstrom Technology in January 2022 to be part of the transatlantic Angstrom Technology Group of Companies. It is joined in the group by UK-based Specific Environments Ltd (SEL) which further enhances sector expertise and capability for cleanrooms, containment, and controlled environments.

Both Nicola and Oliver have been promoted from senior roles at C2C. Nicola was the Head of People, where she shaped the future of the team, and Oliver was Head of Global Cleanroom Solutions, where he influenced the commercial operations within the business.

Joe Govier remains C2C’s CEO, providing support to Nicola and Oliver as they work to continue his legacy of growing one of the most technically-capable and well-known brands in the cleanroom sector.
“C2C is an amazing business, with a proud history and an exciting future. The talent, energy and passion within our team is second to none, and it’s an honour to be asked to lead the next stage of our journey,” says Nicola. “C2C is celebrating 20 years of business this year and as we move forward into this new era within a larger group, we have increased our offerings to satisfy the market. We are excited to have the opportunity to work with very talented colleagues at both Angstrom and SEL.”

As well as its core service of cleanroom design and build, Nicola and Oliver will be driving the C2C team to focus on growing consumables and equipment, and validation services.

For more information about C2C’s cleanroom range and services, please visit

Contamination Control in our New World

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Our World has within the last year has undergone a major change. The Pandemic has brought to the forefront just how important Contamination Control is in respect of Hygiene, fresh air (including filtered air) and the circulation of quality air within premises.

Clean Air can lead to a  healthy environment, mental stability and people performance in the workplace, which at present is a priority in order to keep stress levels down.  Good ventilation and the flow of fresh air with optimum air change rates can reduce the risk of virus and germ transmission.  Coupled with good hygiene practice, this increases your chances of staying healthy in this new world normal, which we have come to know.

There has been a lot of talk about droplets and Aerosol’s, and the differences between them.  This needs some clarification:

Droplet transmission is infection spread through exposure to virus-containing respiratory droplets (i.e., larger and smaller droplets and particles) exhaled by an infectious person.  Transmission is most likely to occur when someone is close to the infectious person, generally within about 6 feet.

Airborne transmission is infection spread through exposure to those virus-containing respiratory droplets comprised of smaller droplets and particles that can remain suspended in the air over long distances (usually greater than 6 feet) and time (typically hours). 

Droplet transmission consists of exposure to larger droplets, smaller droplets, and particles when a person is close to an infected person. Airborne transmission consists of exposure to smaller droplets and particles at greater distances or over longer times.

These modes of transmission are not mutually exclusive.  For instance, “close contact” refers to transmission that can happen by either contact or droplet transmission while a person is within about 6 feet of an infected person.

Scientific Studies and guidelines have historically used a threshold of 5μm to differentiate between large and small particles, but researchers are now suggesting that a size threshold of 100μm better differentiates aerodynamic behaviour of particles, and particles that would fall to the ground within 2 m are likely to be in the 60–100μm in size.  Investigators have also measured particle sizes of infectious aerosols and have shown that pathogens are most commonly found in smaller particles typically (<5μm), which are airborne and can travel further and ingestible in the right circumstances.

SUMMARY: Airborne transmission is different from droplet transmission as it refers to the presence of microbes within droplet nuclei, which are generally considered to be particles <5μm in diameter, these particles can remain in the air for long periods of time and be transmitted to others over distances greater than 1 meter.

As new technologies advance, the Contagious Variants pose a problem if they are not controlled. We need to focus on the impact of these Biological diseases especially the variants and scientifically study the impact they have on human life.

Contamination Control is required to control the spread of such biological diseases.  This, together with new Technology, including containment/quarantine facilities and best hygiene practices which includes certificated high PPE will ensure that we all have a future.

Beckman Coulter on good GMP cleanroom practice

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Environmental Monitoring and Data Integrity

Routine Environmental Monitoring in GMP cleanrooms is a manual process. It can can be complex and typically involves thousands of sample data points per month, manual data transcription and all too frequently technicians have to deal with data gaps and integrity challenges.

Routine Environmental Monitoring programs should be based on a risk assessment of contamination threats to the product during the manufacturing process. The rules for classification do not take this into account i.e. the sampling locations for monitoring may be very different to those used in classifying the room itself and this means that when the risk is identified in the location the product has already been exposed to risk.

The FDA’s ALCOA advice clearly targets manual configuration and data transcription practices.

Are controls in place to ensure that data is complete?

Are activities documented at the time of performance?

Are activities attributable to a specific individual?

Can only authorized individuals make changes to records?

Is there a record of changes to data?

Are records reviewed for accuracy, completeness, and compliance with established standards?

This video clearly shows the stages in this process ..!

Spotlight on – Stuart White, Director of Sanondaf UK Ltd

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Company Name:

Sanondaf UK Ltd


Decontamination using dry fogging technique.  Sanondaf Ltd was set up to become a franchise model and operates in the UK and overseas.

How long have you been a S2C2 member:

I have been involved with the Society since 2014, and became Chairman at the turn of the year.

What does your business do:

Sanondaf have operated as a specialist decontamination company in
the industry since 2014, servicing a range of NHS, Laboratories and University clients.

Has anything changed for your business during the pandemic:

The business has become more widely recognised in the industry since March, with large infrastructure suppliers and government agencies contacting Sanondaf to use our services.  The business has experienced rapid growth in this time, meaning the introduction of six new business owners and the manufacture of 30 new foggers inline with demand.

What are the benefits of being a S2C2 member:

S2C2 is a benchmark for industry professionals to be associated with, being the only UK society to have ICCCS status.  Through membership I have gained knowledge which in turn has translated to new business ideas and contacts.

The Air We Breathe

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PUBLIC HEALTH ENGLAND GUIDANCE ON INFECTION CONTROL states that “The transmission of COVID-19 is thought to occur mainly through respiratory droplets generated by coughing and sneezing, and through contact with contaminated surfaces. The predominant modes of transmission are assumed to be droplet and contact.

Droplets will generally fall out of the airstream within a short distance (depending on airflow speed and direction), hence the guidance to remain 2m apart. However, these may evaporate, reducing in size and mass, and travel further in air streams, contaminating surfaces and increasing the risk of airborne transmission in the way of an aerosol which is made up of very small micron particulates.

While airborne transmission is not thought to be a primary route of transmission, there is an emerging and growing body of evidence that the SARS-CoV-2 can also be spread through the air, particularly in poorly ventilated indoor spaces, and that ventilation provision in buildings should be reviewed in the light of this.

Emerging Findings                                                                              

Proving modes of transmission during an outbreak is difficult. However, multiple recent studies are showing evidence of indirect contact (which may be linked to airborne spread) and have also linked airflow patterns to infection cases.

This has been particularly the case in high occupancy areas, in spaces with little outdoor air, and when people generate a lot of aerosols (e.g. shouting and singing, vigorous exercise). Given the growing body of evidence suggesting airborne transmission may be a route of infection and knowledge of aerosol generation and transport, it is prudent to ensure ventilation within your buildings is operating appropriately to offer some protection to the occupants.

The following measures, using outside air wherever possible, should help to reduce the risks from airborne transmission, but bear in mind the outside air, depending where you are situated, may need to be assessed for its own air quality and dealt with accordingly, say by using better filtration.

Prevention As We Know it

The primary mechanisms for preventing the transmission of coronavirus remain regular, that is thorough hand washing using soap and hot water for at least 20 seconds, the sanitization of your hands using a suitable alcohol based sanitizer. Couple this with strict adherence to social distancing requirements and staying at home as required.

Surfaces which may be contaminated also need regular cleaning following the protocols set out by Public Health England this will involve using good hygiene practices and using a combination of detergents and disinfectants.

The Dilution of internal air within a building should reduce any risk of potential airborne viral transmission by reducing exposure time to any airborne viral aerosols, and also reduce the chance for these aerosols to settle on surfaces. Evidence shows that virus can survive on some surfaces for at least 72 HOURS and hence any action to limit surface contamination is beneficial.

It is recommended that any ventilation or air conditioning system that normally runs with a recirculation mode should now be set up to run on full outside air where this is possible, but your assessments should take into account things like the outside ambient conditions and the filtration used within your Air Handling Units.

In buildings with mechanical ventilation systems extended operation times are recommended. In demand control systems CO2 set points should be set to 400ppm to increase the delivery of outside air. Ventilation should be kept on for longer, with lower ventilation rates when people are absent. It is not recommended to switch ventilation systems off in any buildings, even those temporarily vacated, but to operate them continuously at reduced speeds.

Recirculation of air between spaces, rooms or zones occupied by different people should be avoided. However, in the case of any systems serving a single space, partial recirculation of air within that space, such as through a local fan coil unit, is less of a concern. The reason is that the primary objective is to maximize the air exchange rate with outside air and to minimize the risk of any pockets of stagnant air.

If a local recirculation unit enhances air disturbance and hence helps reduce the risk of stagnant air then this should be considered when developing a strategy. Note that although these are relatively uncommon today, ceiling fans within a space can provide this function.

On colder days consideration must be given to human behavioural responses. A ventilation system on full outside air which is not adequately heated may create discomfort draughts. This may lead to users seeking to turn the system off, or with naturally ventilated spaces users may close vents or windows. These actions will reduce the air exchange rate and dilution of any contaminants (and not just any viral contamination) and overcome the primary objective of the ventilation strategy. It is important that where users can intervene in the control of the ventilation that they are made aware of the benefit of these for reducing the circulation of infectious material.

Care should be taken with any ventilation grills that can be blocked, e.g. floor grilles for displacement ventilation, and occupants educated on the purpose and benefits of these.

The potential benefit to public health at this time outweighs the reduction in energy efficiency caused by not re-circulating air. Airborne contaminants may be minimized by proper and effective filtration and regular maintenance. Viral material that settles in ductwork will become unviable over time. In the event that some viral material entered ventilation and air-conditioning systems prior to buildings being vacated due to the current restrictions, it is extremely unlikely that that material will pose any risk when those buildings are re-occupied.

Where cleaning or planned maintenance of ventilation systems is required, such as in catering premises, it should be undertaken in line with agreed industry guidance, including that relating to site operations under social distancing requirements. Appropriate PPE should be worn and all materials, including old filters, should be carefully bagged and disposed of safely. Given the requirement for many business premises to close for the immediate future, there is unlikely to be a requirement to undertake work on their ventilation or air conditioning systems at this time.

In poorly ventilated spaces with a high occupancy and where it is difficult to increase ventilation rates it may be appropriate to consider using air cleaning and disinfection devices. The most appropriate devices are likely to be local HEPA filtration units or those that use germicidal UV (GUV) radiation. GUV devices use radiation in the UV-C spectrum and have been shown to inactivate coronaviruses, although there is not yet specific evidence of the efficacy of UV-C irradiation for SARS-CoV-2.

There are currently uncertainties about a variety of factors affecting UV performance including dosage, wavelength and exposure time. In addition, consideration will need to address the specific room and system configuration, air flow, distribution and humidity.

Any potential equipment will need to be properly tested, validated and quality assured and demonstrated to provide the specific irradiation properties it is designed to and nothing else. It is essential that appropriate safety interlocks are installed to ensure UV cleaning equipment is not operated when people may be exposed to the radiation.

They can be applied as an upper-room system or a standalone consumer unit, but it is important that these are sized correctly for the room as many do not have the flow rate to be effective in larger spaces. In-duct UV-C is not recommended to control disease transmission unless it is to decontaminate air that is re-circulated.

Devices that emit ozone or other potentially hazardous by-products should not be used in occupied spaces. Further guidance on air cleaning and disinfection is given in CIBSE Guide A.

As mentioned before in several articles the definition of the word droplet and Aerosol, droplets are usually larger particles that fall to ground quite quickly, and aerosols are the finer particulate that can travel further and remain airborne.

The internal air supply and the extraction within buildings plays a vital roll. As when the Air Handling Unit is re-circulating a percentage of its’ air, the smaller aerosols/particulate, could be re-circulating back into other areas/rooms, corridors, lobbies etc.

Filtration plays a vital part of the Air Handling Unit, because ill fitting filters or the wrong filter types, can cause its own problems. This can add to a high contamination of many types of particulates within the area.

The need to look after your AHUs and its’ associated ductwork is paramount. This also includes things like duct work cleaning, drive belt replacements, bearings, coil cleaning and condensate wastes, and more importantly the fresh air intakes.

If total fresh intake is going to be used, then certain factors have to be taken into account. The biggest factor is ‘If I go to total fresh air Intake, can my filters cope with the dirt build up on my filters’ (depending on my Location). Also remember the whole system has been balanced to achieve certain airflows/patterns (where specified) within each area, and also give the correct air change rates according to CIBSE guidelines.

The Air Change rates within buildings play a vital role, especially where you have classrooms, libraries, Gyms, shopping Mals etc. and areas of high occupancy/footfall.

Remember the outside air is not filtered, and depending where you are located this has a major impact on your Air Handling Systems and the internal air within the building. Because the only thing between you and the outside is the Filtration that is installed within the AHUs and if these are not fitted correctly or are the wrong grade, then the air being delivered into your buildings will not be clean.


Keith Wallace, Envirofil Ltd

Sonovia launches face mask business in the UK

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Sonovia is launching its face masks in the UK.

In development for more than seven years, the masks have been proven to be over 90% effective against COVID-19, the company says. The patented technology infuses Zinc Oxide nanoparticles into the fabric, and is designed to boost both the masks’ sustainability and their efficacy.

While it’s easy to see why during a healthcare crisis, the environmental crisis takes a back seat, recent figures suggest damage caused by the volume unrecyclable masks being dumped across the UK is an environmental emergency waiting to happen, Sonovia says.

As the B2B distributor for Sonovia’s products in the UK, GlobalNPD says it aims to make “innovative frontier technologies” more accessible and help the world adjust to the post-COVID landscape.

Dr Jeevan Boyal, a director of GlobalNPD, said: “We’re proud to launch Sonovia’s masks into the UK market via GlobalNPD and hope that the products help businesses and consumers alike in adjusting to the new normal. We have seen the numerous reports of environmental impact of non-reusable masks, and if we continue ignoring it for much longer the impact will go beyond what can be repaired.

“Sonovia’s revolutionary technology took over seven years to develop because we were not willing to compromise on functionality or sustainability whilst keeping in mind our competitive price point and appeal to the B2B audience. Ultimately our mission is to bring frontier products led by superior technology to global audiences, and our roll out in the UK is the next piece of our puzzle.”

S2C2 Training Courses – Spring 2020

By Events, News
  • 19 February 2020 : Cleanroom Validation Testing Course
  • 20 February 2020 : Choosing & Validating a Garment System for Aseptic Applications
  • 20 February 2020 : Particle Counting
  • 21 February 2020 : Cleanroom Cleaning Course
  • 21 February 2020 : Cleanroom Behaviour Course

To book visit our Training Courses page and choose the course you are interested in.

Cleanroom Validation Testing Course a great success

By News
The recent Cleanroom validation testing course was a great success with attendees from all parts of Europe.
S2C2 are pleased to announce that they will be running this course again in 2020 – on Wednesday 19th February.
Visit our courses section to book your place now.

S2C2 training courses now available

By News

The society is very aware of the value of training and over the next few months and years we are planning to run courses that will go back to basics. In this mature industry some simple aspects of cleanroom procedures are not understood correctly and we want to address this.

We have revamped our website to make it more relevant and accessible to members. In addition to the variety of courses that are now available to book, over the coming months there will be news of these and future planned courses which will include hands on training given in local areas throughout the UK.
I have always been uncomfortable about certifying anyone. Attending a training course is one thing but giving them a certificate certifying they are competent to carry out complex procedures has never sat comfortably with me. True competence can only be gained over a period from on the job experience using a wide range of equipment and different techniques.

Jim Carmichael, Chairman